Epimerization of moxalactam by albumin and simulation of in vivo epimerization by a physiologically based pharmacokinetic model

Application of a Physiologically Based Pharmacokinetic Model to Assess Propofol Hepatic and Renal Glucuronidation in Isolation: Utility of In Vitro and In Vivo Data

Drug Metabolism and Disposition ◽

10.1124/dmd.112.050294 ◽

2013 ◽

Vol 41 (4) ◽

pp. 744-753 ◽

Cited By ~ 15

Author(s):

Katherine L. Gill ◽

Michael Gertz ◽

J. Brian Houston ◽

Aleksandra Galetin

Keyword(s):

Pharmacokinetic Model ◽

Simulation of Toluene Kinetics in the Rat by a Physiologically Based Pharmacokinetic Model with Application of Biotransformation Parameters Derived Independently in Vitro and in Vivo

Toxicological Sciences ◽

10.1093/toxsci/32.2.260 ◽

1996 ◽

Vol 32 (2) ◽

pp. 260-268

Author(s):

JOOST DEJONGH ◽

BAS J. BLAAUBOER

Keyword(s):

Pharmacokinetic Model ◽

A physiologically based pharmacokinetic model to predict the superparamagnetic iron oxide nanoparticles (SPIONs) accumulation in vivo

nano Online ◽

10.1515/nano.0012.00072 ◽

2018 ◽

Author(s):

Adny Henrique Silva ◽

Enio Lima Jr ◽

Marcelo Vasquez Mansilla ◽

Roberto Daniel Zysler ◽

Mary Luz Mojica Pisciotti ◽

...

Keyword(s):

Iron Oxide ◽

Iron Oxide Nanoparticles ◽

Pharmacokinetic Model ◽

Superparamagnetic Iron Oxide ◽

Superparamagnetic Iron Oxide Nanoparticles ◽

Oxide Nanoparticles ◽

Elucidating the in vivo fate of nanocrystals using a physiologically based pharmacokinetic model: a case study with the anticancer agent SNX-2112

International Journal of Nanomedicine ◽

10.2147/ijn.s79734 ◽

2015 ◽

pp. 2521 ◽

Cited By ~ 4

Author(s):

Baojian Wu ◽

Dong Dong ◽

Xiao Wang ◽

Huailing Wang ◽

Xingwang Zhang ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Anticancer Agent ◽

Development of a Physiologically Based Pharmacokinetic Model for Sinogliatin, a First-in-Class Glucokinase Activator, by Integrating Allometric Scaling, In Vitro to In Vivo Exploration and Steady-State Concentration–Mean Residence Time Methods: Mechanistic Understanding of its Pharmacokinetics

Clinical Pharmacokinetics ◽

10.1007/s40262-018-0631-z ◽

2018 ◽

Vol 57 (10) ◽

pp. 1307-1323 ◽

Cited By ~ 4

Author(s):

Ling Song ◽

Yi Zhang ◽

Ji Jiang ◽

Shuang Ren ◽

Li Chen ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Allometric Scaling ◽

Steady State Concentration ◽

Glucokinase Activator ◽

Physiologically Based ◽

State Concentration

Combining an In Vitro Kinetic Model with a Physiologically-Based Pharmacokinetic Model to Assess the Potential In Vivo Fate of Polyvinyl Pyrrolidone-Vinyl Acetate Copolymers

Pharmaceutical Research ◽

10.1007/s11095-017-2305-1 ◽

2018 ◽

Vol 35 (4) ◽

Author(s):

Daniel S. Hsieh ◽

Liang Luo ◽

Yan Xu ◽

Joshua D. Engstrom ◽

Qi Gao

Keyword(s):

Kinetic Model ◽

Vinyl Acetate ◽

Pharmacokinetic Model ◽

Polyvinyl Pyrrolidone ◽

Biopharmaceutic In Vitro In Vivo Extrapolation (IVIV_E) Informed Physiologically-Based Pharmacokinetic Model of Ritonavir Norvir Tablet Absorption in Humans Under Fasted and Fed State Conditions

Molecular Pharmaceutics ◽

10.1021/acs.molpharmaceut.0c00043 ◽

2020 ◽

Vol 17 (7) ◽

pp. 2329-2344 ◽

Cited By ~ 4

Author(s):

Sumit Arora ◽

Amita Pansari ◽

Peter Kilford ◽

Masoud Jamei ◽

Iain Gardner ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Fed State ◽

Physiologically Based ◽

In Vivo Extrapolation

Development of a Physiologically-Based Pharmacokinetic Model for Preterm Neonates: Evaluation with In Vivo Data

Current Pharmaceutical Design ◽

10.2174/1381612821666150901110533 ◽

2015 ◽

Vol 21 (39) ◽

pp. 5688-5698 ◽

Cited By ~ 33

Author(s):

Karina Claassen ◽

Kirstin Thelen ◽

Katrin Coboeken ◽

Thomas Gaub ◽

Jorg Lippert ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Preterm Neonates ◽

Physiologically Based Pharmacokinetic Model for Tetrachlorobenzyltoluenes in Rat: Comparison of in Vitro and in Vivo Metabolic Rates

Toxicological Sciences ◽

10.1093/toxsci/63.1.22 ◽

2001 ◽

Vol 63 (1) ◽

pp. 22-28 ◽

Cited By ~ 9

Author(s):

H. J. Kramer

Keyword(s):

Pharmacokinetic Model ◽

Metabolic Rates ◽

Physiologically Based Pharmacokinetic Model for Composite Nanodevices: Effect of Charge and Size on In Vivo Disposition

Pharmaceutical Research ◽

10.1007/s11095-012-0784-7 ◽

2012 ◽

Vol 29 (9) ◽

pp. 2534-2542 ◽

Cited By ~ 21

Author(s):

Donald E. Mager ◽

Vidhi Mody ◽

Chao Xu ◽

Alan Forrest ◽

Wojciech G. Lesniak ◽

...

Keyword(s):

Pharmacokinetic Model ◽